X-ray diffraction
2.85Å resolution

CTBP/BARS in ternary complex with NAD(H) and RRTGAPPAL peptide


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
C-terminal binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 358 amino acids
Theoretical weight: 39.51 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
  • Canonical: Q6AZ26 (Residues: 1-350; Coverage: 90%)
Gene name: Ctbp1
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain
Zinc finger protein 217 Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 940 Da
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: O75362 (Residues: 752-760; Coverage: 1%)
Gene names: ZABC1, ZNF217

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P6422
Unit cell:
a: 89.31Å b: 89.31Å c: 162.72Å
α: 90° β: 90° γ: 120°
R R work R free
0.232 0.227 0.275
Expression systems:
  • Escherichia coli
  • Not provided