2grc

X-ray diffraction
1.5Å resolution

1.5 A structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF remodeling complex

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription activator BRG1 Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 15.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P51532 (Residues: 1448-1575; Coverage: 8%)
Gene names: BAF190A, BRG1, SMARCA4, SNF2B, SNF2L4
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P21
Unit cell:
a: 29.86Å b: 30.33Å c: 66.82Å
α: 90° β: 90.28° γ: 90°
R-values:
R R work R free
0.25 0.242 0.264
Expression system: Escherichia coli BL21(DE3)