PDBe 2gjk

X-ray diffraction
2.6Å resolution

Structural and functional insights into the human Upf1 helicase core

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulator of nonsense transcripts 1 Chain: A
Molecule details ›
Chain: A
Length: 624 amino acids
Theoretical weight: 70.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt: Gene names: KIAA0221, RENT1, UPF1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P43212
Unit cell:
a: 188.979Å b: 188.979Å c: 44.872Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.245 0.271
Expression system: Escherichia coli