2gdc

X-ray diffraction
2.74Å resolution

Structure of Vinculin VD1 / IpaA560-633 complex

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin Chain: A
Molecule details ›
Chain: A
Length: 266 amino acids
Theoretical weight: 29.79 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P12003 (Residues: 1-266; Coverage: 23%)
Gene names: VCL, VINC1
Structure domains: Alpha-catenin/vinculin-like
Invasin IpaA Chain: B
Molecule details ›
Chain: B
Length: 21 amino acids
Theoretical weight: 2.1 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli
UniProt:
  • Canonical: P18010 (Residues: 612-630; Coverage: 3%)
Gene names: CP0125, ipaA

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P21212
Unit cell:
a: 52.684Å b: 68.326Å c: 96.521Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.247 0.294
Expression system: Escherichia coli