X-ray diffraction
1.8Å resolution

Crystal Structure of Rv1846c, a Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Transcriptional regulator BlaI Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.39 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21
  • Canonical: P9WMJ5 (Residues: 1-138; Coverage: 100%)
Gene names: Rv1846c, blaI
Sequence domains: Penicillinase repressor
Structure domains:

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 60.58Å b: 64.33Å c: 75.75Å
α: 90° β: 90° γ: 90°
R R work R free
0.204 0.202 0.252
Expression system: Escherichia coli BL21