Solution NMR

NMR solution structure of the PHD domain from the human BPTF in complex with H3(1-15)K4me3 peptide


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nucleosome-remodeling factor subunit BPTF Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 7.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q12830 (Residues: 2865-2921; Coverage: 2%)
Gene names: BPTF, FAC1, FALZ
Sequence domains: PHD-finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
Histone H3 Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.61 KDa
Source organism: Hemicentrotus pulcherrimus
Expression system: Not provided
  • Canonical: Q7M3Z9 (Residues: 1-15; Coverage: 75%)

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Refinement method: The structure was solved using a torsion angle simulated annealing protocol
Expression systems:
  • Escherichia coli
  • Not provided