› 2fri

X-ray diffraction
1.6Å resolution

Horse Heart Myoglobin, Nitrite Adduct, Co-crystallized

Released:
DOI: 10.2210/pdb2fri/pdb
PDB entry 2fri coloured by chain, front view.
PDB entry 2fri coloured by chain, side view.
PDB entry 2fri coloured by chain, top view.
Source organism: Equus caballus
Primary publication:
Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin.
Copeland DM, Soares AS, West AH, Richter-Addo GB
J Inorg Biochem 100 1413-25 (2006)
PMID: 16777231

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159278 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myoglobin Chain: X
Molecule details ›
Chain: X
Length: 153 amino acids
Theoretical weight: 16.98 KDa
Source organism: Equus caballus
UniProt:
  • Canonical: P68082 (Residues: 2-154; Coverage: 99%)
Gene name: MB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

3 bound ligands:
Ligand NO2 1 x NO2
Ligand SO4 2 x SO4
Ligand HEM 1 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 35.223Å b: 28.592Å c: 62.841Å
α: 90° β: 106.03° γ: 90°
R-values:
R R work R free
0.149 0.146 0.206

Quick links

Citations

7 review citations

Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species.
Fukuto et al. (2012)
6 more

2 mentions without citation

Reversible thermally induced spin crossover in the myoglobin-nitrito adduct directly monitored by resonance Raman spectroscopy.
Valianti et al. (2023)
1 more