2fn4

X-ray diffraction
1.65Å resolution

The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state

Released:
Source organism: Homo sapiens
Entry authors: Turnbull AP, Elkins JM, Gileadi C, Burgess N, Salah E, Papagrigoriou E, Debreczeni J, von Delft F, Weigelt J, Edwards A, Arrowsmith C, Sundstrom M, Doyle D, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein R-Ras Chain: A
Molecule details ›
Chain: A
Length: 181 amino acids
Theoretical weight: 20.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10301 (Residues: 23-201; Coverage: 82%)
Gene name: RRAS
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 43.152Å b: 43.152Å c: 155.499Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.215 0.251
Expression system: Escherichia coli