Function and Biology Details
Release of N-terminal proline from a peptide.
Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.
An (L-cysteinylglycine)-S-conjugate + H(2)O = an L-cysteine-S-conjugate + glycine
Structure analysis Details
Length: 486 amino acids
Theoretical weight: 52.87 KDa
Source organism: Bos taurus
- Canonical: P00727 (Residues: 33-518; Coverage: 94%)
Sequence domains: Cytosol aminopeptidase family, catalytic domain