Function and Biology Details
Reactions catalysed:
Cleaves the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Endonuclease V (preferred)
PDBe Complex ID:
PDB-CPX-137634 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endonuclease V
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 16.1 KDa
Source organism: Escherichia virus T4
Expression system: Not provided
UniProt:
Structure domains: T4 endonuclease V
Length: 138 amino acids
Theoretical weight: 16.1 KDa
Source organism: Escherichia virus T4
Expression system: Not provided
UniProt:
- Canonical:
P04418 (Residues: 1-138; Coverage: 100%)
Structure domains: T4 endonuclease V
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Spacegroup:
P21
Expression system: Not provided
