2ej4

Solution NMR

Functional and structural basis of nuclear localization signal in ZIC3 zinc finger domain: a role of conserved tryptophan residue in the zinc finger domain

Released:
Source organism: Homo sapiens
Entry authors: Tomizawa T, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger protein ZIC 3 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.63 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O60481 (Residues: 245-326; Coverage: 18%)
Gene names: ZIC3, ZNF203
Sequence domains: Zinc finger, C2H2 type
Structure domains: Classic Zinc Finger

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided