2egn

X-ray diffraction
2.4Å resolution

Crystal Structure of Tamalin PDZ Domain in Complex with mGluR5 C-terminal Peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
Non-polymer only tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
General receptor for phosphoinositides 1-associated scaffold protein Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 10.64 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8R4T5 (Residues: 96-189; Coverage: 24%)
Gene names: Grasp, Tamalin
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
mGluR5 C-terminal peptide Chain: B
Molecule details ›
Chain: B
Length: 5 amino acids
Theoretical weight: 479 Da
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: I422
Unit cell:
a: 75.61Å b: 75.61Å c: 80.185Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.259 0.259 0.273
Expression system: Escherichia coli BL21