› 2eck

X-ray diffraction
2.8Å resolution

STRUCTURE OF PHOSPHOTRANSFERASE

Released:
DOI: 10.2210/pdb2eck/pdb
PDB entry 2eck coloured by chain, front view.
PDB entry 2eck coloured by chain, side view.
PDB entry 2eck coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure of ADP/AMP complex of Escherichia coli adenylate kinase.
Berry MB, Bae E, Bilderback TR, Glaser M, Phillips GN
Proteins 62 555-6 (2006)
PMID: 16302237

Function and Biology Details

Reaction catalysed: 
ATP + AMP = 2 ADP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159587 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 214 amino acids
Theoretical weight: 23.62 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P69441 (Residues: 1-214; Coverage: 100%)
Gene names: JW0463, adk, b0474, dnaW, plsA
Sequence domains:
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand AMP 2 x AMP
Ligand ADP 2 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: P21212
Unit cell:
a: 73.5Å b: 84.8Å c: 80.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.276
Expression system: Escherichia coli

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Citations

1 review citation

Moving beyond static snapshots: Protein dynamics and the Protein Data Bank.
Miller et al. (2021)
15 other articles

16 mentions without citation

Strategies for the Production of Molecular Animations.
Werner E. (2022)
15 more