2e4h

Solution NMR

Solution structure of cytoskeletal protein in complex with tubulin tail

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CAP-Gly domain-containing linker protein 1 Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P30622 (Residues: 203-300; Coverage: 7%)
Gene names: CLIP1, CYLN1, RSN
Sequence domains: CAP-Gly domain
Structure domains: CAP Gly-rich-like domain
Detyrosinated tubulin alpha-1B chain Chain: B
Molecule details ›
Chain: B
Length: 36 amino acids
Theoretical weight: 4.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68363 (Residues: 416-451; Coverage: 8%)
Gene name: TUBA1B

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli BL21
  • Escherichia coli