PDBe 2e3n

X-ray diffraction
1.4Å resolution

Crystal structure of CERT START domain in complex with C6-ceramide (P212121)

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen type IV alpha-3-binding protein Chain: A
Molecule details ›
Chain: A
Length: 255 amino acids
Theoretical weight: 28.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y5P4 (Residues: 347-624; Coverage: 40%)
  • Best match: Q9Y5P4-2 (Residues: 347-598)
Gene names: CERT, COL4A3BP, STARD11
Sequence domains: START domain
Structure domains: Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P212121
Unit cell:
a: 54.423Å b: 55.195Å c: 93.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.216 0.225
Expression system: Escherichia coli