2dok

X-ray diffraction
1.8Å resolution

Crystal structure of the PIN domain of human EST1A

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomerase-binding protein EST1A Chains: A, B
Molecule details ›
Chains: A, B
Length: 186 amino acids
Theoretical weight: 21.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86US8 (Residues: 1239-1419; Coverage: 13%)
Gene names: C17orf31, EST1A, KIAA0732, SMG6
Sequence domains: PIN domain
Structure domains: 5'-nuclease

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: C2
Unit cell:
a: 107.326Å b: 51.586Å c: 100.48Å
α: 90° β: 119.25° γ: 90°
R-values:
R R work R free
0.215 0.213 0.254
Expression system: Escherichia coli