2d6p

X-ray diffraction
2.7Å resolution

Crystal structure of mouse galectin-9 N-terminal CRD in complex with T-antigen

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 159 amino acids
Theoretical weight: 18.17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O08573 (Residues: 1-147; Coverage: 42%)
  • Best match: O08573-2 (Residues: 1-157)
Gene name: Lgals9
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P41212
Unit cell:
a: 58.051Å b: 58.051Å c: 222.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.237 0.296
Expression system: Escherichia coli BL21(DE3)