Solution NMR

Solution structure of the NRSF/REST-mSin3B PAH1 complex


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Paired amphipathic helix protein Sin3b Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 8.81 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q62141 (Residues: 31-107; Coverage: 7%)
Gene names: Kiaa0700, Sin3b
Sequence domains: Paired amphipathic helix repeat
Structure domains: Paired amphipathic helix
RE1-silencing transcription factor Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q13127 (Residues: 43-57; Coverage: 1%)
Gene names: NRSF, REST, XBR

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Chemical shifts: BMR6749  
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided