2cqg

Solution NMR

Solution structure of the RNA binding domain of TAR DNA-binding protein-43

Released:
Source organism: Homo sapiens
Entry authors: Suzuki S, Muto Y, Inoue M, Kigawa T, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TAR DNA-binding protein 43 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13148 (Residues: 96-185; Coverage: 22%)
Gene names: TARDBP, TDP43
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dyanamics, simulated annealing
Expression system: Not provided