PDBe 2cde

X-ray diffraction
3.5Å resolution

Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
INKT-TCR Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 192 amino acids
Theoretical weight: 21.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
Structure domains: Immunoglobulins
T cell receptor beta constant 1 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 244 amino acids
Theoretical weight: 27.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Gene name: TRBC1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2
Unit cell:
a: 289.36Å b: 84.95Å c: 78.86Å
α: 90° β: 103.3° γ: 90°
R-values:
R R work R free
0.283 0.283 0.35
Expression system: Escherichia coli BL21(DE3)