X-ray diffraction
1.09Å resolution

Crystal Structure Of Human Inosine Triphosphatase


Function and Biology Details

Reaction catalysed:
A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Inosine triphosphate pyrophosphatase Chains: A, B
Molecule details ›
Chains: A, B
Length: 196 amino acids
Theoretical weight: 21.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9BY32 (Residues: 1-194; Coverage: 100%)
Gene names: C20orf37, ITPA, My049, OK/SW-cl.9
Sequence domains: Ham1 family
Structure domains: Maf protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21
Unit cell:
a: 31.23Å b: 105Å c: 50.14Å
α: 90° β: 90.01° γ: 90°
R R work R free
0.097 not available 0.153
Expression system: Escherichia coli BL21(DE3)