2c9o

X-ray diffraction
2.2Å resolution

3D Structure of the human RuvB-like helicase RuvBL1

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem. 281 38918-29 (2006)
PMID: 17060327

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RuvB-like 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 456 amino acids
Theoretical weight: 50.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y265 (Residues: 1-456; Coverage: 100%)
Gene names: INO80H, NMP238, RUVBL1, TIP49, TIP49A
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P6
Unit cell:
a: 207.08Å b: 207.08Å c: 60.71Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.206 0.257
Expression system: Escherichia coli BL21(DE3)