› 2c4d

X-ray diffraction
2.6Å resolution

2.6A Crystal Structure of Psathyrella velutina Lectin in Complex with N-acetylglucosamine

Released:
DOI: 10.2210/pdb2c4d/pdb
PDB entry 2c4d coloured by chain, front view.
PDB entry 2c4d coloured by chain, side view.
PDB entry 2c4d coloured by chain, top view.
Source organism: Lacrymaria velutina
Primary publication:
Beta-propeller crystal structure of Psathyrella velutina lectin: an integrin-like fungal protein interacting with monosaccharides and calcium.
Cioci G, Mitchell EP, Chazalet V, Debray H, Oscarson S, Lahmann M, Gautier C, Breton C, Perez S, Imberty A
J Mol Biol 357 1575-91 (2006)
PMID: 16497330

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174236 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lectin PVL Chain: A
Molecule details ›
Chain: A
Length: 401 amino acids
Theoretical weight: 43.02 KDa
Source organism: Lacrymaria velutina
UniProt:
  • Canonical: Q309D1 (Residues: 1-395; Coverage: 100%)
Gene name: pvl
Sequence domains: FG-GAP-like repeat

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand NAG 6 x NAG
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P3121
Unit cell:
a: 106.767Å b: 106.767Å c: 86.622Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.202 0.271

Quick links

Citations

9 review citations

Bioactive proteins from mushrooms.
Xu et al. (2011)
8 more

3 mentions without citation

Mushroom lectins: specificity, structure and bioactivity relevant to human disease.
Hassan et al. (2015)
2 more