› 2bv7

X-ray diffraction
1.79Å resolution

Crystal structure of GLTP with bound GM3

Released:
DOI: 10.2210/pdb2bv7/pdb
PDB entry 2bv7 coloured by chain, front view.
PDB entry 2bv7 coloured by chain, side view.
PDB entry 2bv7 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structural evidence for adaptive ligand binding of glycolipid transfer protein.
Airenne TT, Kidron H, Nymalm Y, Nylund M, West G, Mattjus P, Salminen TA
J Mol Biol 355 224-36 (2006)
PMID: 16309699

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159365 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycolipid transfer protein Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.82 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P68265 (Residues: 2-209; Coverage: 100%)
Gene name: GLTP
Sequence domains: Glycolipid transfer protein (GLTP)
Structure domains: Glycolipid transfer protein

Ligands and Environments

2 bound ligands:
Ligand SO4 2 x SO4
Ligand GM3 1 x GM3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 55.5Å b: 34.6Å c: 58.3Å
α: 90° β: 116.5° γ: 90°
R-values:
R R work R free
0.193 0.189 0.257
Expression system: Escherichia coli BL21

Quick links

Citations

7 review citations

Glycolipid transfer proteins.
Brown et al. (2007)
6 more

3 mentions without citation

Atomic-resolution conformational analysis of the GM3 ganglioside in a lipid bilayer and its implications for ganglioside-protein recognition at membrane surfaces.
DeMarco et al. (2009)
2 more