PDBe 2br9

X-ray diffraction
1.75Å resolution

14-3-3 Protein Epsilon (Human) Complexed to Peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein epsilon Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 26.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62258 (Residues: 1-233; Coverage: 91%)
Gene name: YWHAE
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS Chain: P
Molecule details ›
Chain: P
Length: 7 amino acids
Theoretical weight: 953 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2221
Unit cell:
a: 78.011Å b: 81.533Å c: 80.966Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.239
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided