PDBe 2axh

X-ray diffraction
2.7Å resolution

Crystal structures of T cell receptor beta chains related to rheumatoid arthritis

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo 12-mer
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T cell receptor beta constant 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 242 amino acids
Theoretical weight: 27.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Gene name: TRBC1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P6322
Unit cell:
a: 187.334Å b: 187.334Å c: 86.279Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.237 0.237 0.28
Expression system: Escherichia coli