X-ray diffraction
2.09Å resolution

Detection of new binding site in the C-terminal lobe of lactoferrin:Crystal structure of the complex formed between bovine lactoferrin and a tetrasaccharide at 2.1A resolution

Source organism: Bos taurus
Entry authors: Singh N, Jabeen T, Sharma S, Bhushan A, Singh TP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 38.03 KDa
Source organism: Bos taurus
  • Canonical: P24627 (Residues: 361-708; Coverage: 51%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, NDG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 63.508Å b: 50.518Å c: 66.114Å
α: 90° β: 107.76° γ: 90°
R R work R free
0.211 0.198 0.212