PDBe 2ajv

X-ray diffraction
1.5Å resolution

Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 216 amino acids
Theoretical weight: 24.06 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-104; Coverage: 97%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Vh gene product Chain: H
Molecule details ›
Chain: H
Length: 219 amino acids
Theoretical weight: 23.87 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: A2NUE8 (Residues: 19-117, 118-149; Coverage: 99%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2221
Unit cell:
a: 90.254Å b: 117.32Å c: 85.217Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.227