PDBe 2aju

X-ray diffraction
1.5Å resolution

Cyrstal structure of cocaine catalytic antibody 7A1 Fab'


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 216 amino acids
Theoretical weight: 24.06 KDa
Source organism: Mus musculus
  • Canonical: P01837 (Residues: 1-104; Coverage: 97%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
IgG-2a protein Chain: H
Molecule details ›
Chain: H
Length: 219 amino acids
Theoretical weight: 23.87 KDa
Source organism: Mus musculus
  • Canonical: Q5M842 (Residues: 20-50, 51-124, 125-236; Coverage: 49%)
Gene name: IgG-2a
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2221
Unit cell:
a: 89.797Å b: 117.256Å c: 85.984Å
α: 90° β: 90° γ: 90°
R R work R free
0.184 0.181 0.228