PDBe 2ajs

X-ray diffraction
1.7Å resolution

Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 216 amino acids
Theoretical weight: 24.06 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-104; Coverage: 97%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
IgG-2a protein Chain: H
Molecule details ›
Chain: H
Length: 219 amino acids
Theoretical weight: 23.87 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q5M842 (Residues: 20-50, 51-124, 125-236; Coverage: 49%)
Gene name: IgG-2a
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P43212
Unit cell:
a: 88.107Å b: 88.107Å c: 135.397Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.209 0.233