2acm

Solution NMR

Solution structure of the SEA domain of human mucin 1 (MUC1)

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mucin-1 subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 66 amino acids
Theoretical weight: 7.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15941 (Residues: 1041-1097; Coverage: 5%)
  • Best match: P15941-17 (Residues: 63-106)
Gene names: MUC1, PUM
Structure domains: SEA domain
Mucin-1 subunit beta Chain: B
Molecule details ›
Chain: B
Length: 55 amino acids
Theoretical weight: 6.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15941 (Residues: 1098-1152; Coverage: 5%)
Gene names: MUC1, PUM

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli