2a73

X-ray diffraction
3.3Å resolution

Human Complement Component C3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement C3 beta chain Chain: A
Molecule details ›
Chain: A
Length: 643 amino acids
Theoretical weight: 71.27 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 23-665; Coverage: 39%)
Gene names: C3, CPAMD1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: I222
Unit cell:
a: 116.98Å b: 156.26Å c: 271.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.23 0.289