PDBe 1zsx

X-ray diffraction
1.9Å resolution

Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2)

Released:
Source organism: Homo sapiens
Entry authors: Wennerstrand P, Johannsson I, Ugochukwu E, Kavanagh K, Edwards A, Arrowsmith C, Williams L, Sundstrom M, Guo K, von Delft F, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-gated potassium channel subunit beta-2 Chain: A
Molecule details ›
Chain: A
Length: 347 amino acids
Theoretical weight: 38.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13303 (Residues: 39-360; Coverage: 88%)
Gene names: KCNA2B, KCNAB2, KCNK2
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: I422
Unit cell:
a: 113.231Å b: 113.231Å c: 142.505Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.146 0.145 0.172
Expression system: Escherichia coli BL21(DE3)