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DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (15 MILLIMOLAR)

X-ray diffraction
3.2Å resolution
PDB entry 1zqc coloured by chain, front view.
PDB entry 1zqc coloured by chain, side view.
PDB entry 1zqc coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero trimer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: DNA polymerase beta and DNA
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Multimeric state: hetero trimer
Accessible surface area: 19343.83 Å2
Buried surface area: 2173.77 Å2
Dissociation area: 590.22 Å2
Dissociation energy (ΔGdiss): 6.66 kcal/mol
Dissociation entropy (TΔSdiss): 8.87 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-114934

Macromolecules

DNA polymerase beta
Chain: A
Length: 335 amino acids
Theoretical weight: 38.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06746 (Residues: 1-335; Coverage: 100%)
Gene name: POLB
Pfam:
InterPro:
CATH:
SCOP:
DNA polymerase beta in PDB entry 1zqc, assembly 1, front view.
DNA polymerase beta in PDB entry 1zqc, assembly 1, side view.
DNA polymerase beta in PDB entry 1zqc, assembly 1, top view.
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DNA chain T
Name: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3')
Representative chains: T
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 8 nucleotides
Theoretical weight: 2.43 KDa
DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3') in PDB entry 1zqc, assembly 1, front view.
DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3') in PDB entry 1zqc, assembly 1, side view.
DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3') in PDB entry 1zqc, assembly 1, top view.
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DNA chain P
Name: DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3')
Representative chains: P
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 7 nucleotides
Theoretical weight: 2.11 KDa
DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3') in PDB entry 1zqc, assembly 1, front view.
DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3') in PDB entry 1zqc, assembly 1, side view.
DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3') in PDB entry 1zqc, assembly 1, top view.
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