› 1zm0

X-ray diffraction
2.1Å resolution

Crystal Structure of the Carboxyl Terminal PH Domain of Pleckstrin To 2.1 Angstroms

Released:
DOI: 10.2210/pdb1zm0/pdb
PDB entry 1zm0 coloured by chain, front view.
PDB entry 1zm0 coloured by chain, side view.
PDB entry 1zm0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the carboxy-terminal PH domain of pleckstrin at 2.1 Angstroms.
Jackson SG, Zhang Y, Bao X, Zhang K, Summerfield R, Haslam RJ, Junop MS
Acta Crystallogr D Biol Crystallogr 62 324-30 (2006)
PMID: 16510979

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-140179 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pleckstrin Chains: A, B
Molecule details ›
Chains: A, B
Length: 114 amino acids
Theoretical weight: 13.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08567 (Residues: 240-350; Coverage: 32%)
Gene names: P47, PLEK
Sequence domains: PH domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P41212
Unit cell:
a: 54.572Å b: 54.572Å c: 148.213Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.236 0.244
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 citation in other articles

Structure-function study of the N-terminal domain of exocyst subunit Sec3.
Baek et al. (2010)
1 more

3 mentions without citation

Emerging Roles of Pleckstrin-2 Beyond Cell Spreading.
Wang et al. (2021)
2 more