Solution NMR

NMR Structure of Unphosphorylated Human Phospholamban Pentamer

Source organism: Homo sapiens
Primary publication:
The structure of phospholamban pentamer reveals a channel-like architecture in membranes.
Proc. Natl. Acad. Sci. U.S.A. 102 10870-5 (2005)
PMID: 16043693

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Cardiac phospholamban Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 52 amino acids
Theoretical weight: 6.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P26678 (Residues: 1-52; Coverage: 100%)
Gene names: PLB, PLN
Sequence domains: Phospholamban
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Simulated Annealing, Molecular Dynamics
Expression system: Escherichia coli BL21(DE3)