X-ray diffraction
2.9Å resolution

Crystal structure of G alpha 12 in complex with GDP, Mg2+ and AlF4-


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Guanine nucleotide-binding protein subunit alpha-12 Chains: A, B
Molecule details ›
Chains: A, B
Length: 359 amino acids
Theoretical weight: 41.95 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
  • Canonical: P27600 (Residues: 25-31, 32-47, 48-379; Coverage: 94%)
Gene names: Gna-12, Gna12
Sequence domains: G-protein alpha subunit
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 57.501Å b: 85.23Å c: 82.885Å
α: 90° β: 106.09° γ: 90°
R R work R free
0.239 0.236 0.296
Expression system: Spodoptera frugiperda