Function and Biology Details
Reactions catalysed:
7,8-dihydroneopterin + O(2) = 7,8-dihydroxanthopterin + formate + glycolaldehyde
7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde
7,8-dihydroneopterin = 7,8-dihydromonapterin
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Dihydroneopterin aldolase (preferred)
PDBe Complex ID:
PDB-CPX-161849 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydroneopterin aldolase
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.57 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
Sequence domains: Dihydroneopterin aldolase
Structure domains: GTP Cyclohydrolase I, domain 2
Length: 133 amino acids
Theoretical weight: 14.57 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
- Canonical:
P9WNC5 (Residues: 1-133; Coverage: 100%)
Sequence domains: Dihydroneopterin aldolase
Structure domains: GTP Cyclohydrolase I, domain 2
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X8C
Spacegroup:
I4
Expression system: Escherichia coli
