Function and Biology

Crystal Structure of Human Placental Lactogen

Source organism: Homo sapiens
Biochemical function: metal ion binding
Biological process: growth hormone receptor signaling pathway
Cellular component: vesicle

Sequence family

Pfam Protein family (Pfam)
PF00103
Domain description: Somatotropin hormone family
Occurring in:
  1. Chorionic somatomammotropin hormone 1
The deposited structure of PDB entry 1z7c contains 1 copy of Pfam domain PF00103 (Somatotropin hormone family) in Chorionic somatomammotropin hormone 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001400
Domain description: Somatotropin/prolactin
Occurring in:
  1. Chorionic somatomammotropin hormone 1
IPR018116
Domain description: Somatotropin hormone, conserved site
Occurring in:
  1. Chorionic somatomammotropin hormone 1
IPR009079
Domain description: Four-helical cytokine-like, core
Occurring in:
  1. Chorionic somatomammotropin hormone 1
IPR034975
Domain description: Somatotropin
Occurring in:
  1. Chorionic somatomammotropin hormone 1

Structure domain

CATH CATH domain
1.20.1250.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Growth Hormone; Chain: A;
Homology: Growth Hormone; Chain: A;
Occurring in:
  1. Chorionic somatomammotropin hormone 1
The deposited structure of PDB entry 1z7c contains 1 copy of CATH domain 1.20.1250.10 (Growth Hormone; Chain: A;) in Chorionic somatomammotropin hormone 1. Showing 1 copy in chain A.