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Crystal Structure of the Thrombospondin-1 N-terminal domain

X-ray diffraction
1.8Å resolution
PDB entry 1z78 coloured by chain, front view.
PDB entry 1z78 coloured by chain, side view.
PDB entry 1z78 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Thrombospondin-1
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Multimeric state: monomeric
Accessible surface area: 10059.01 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-139878

Macromolecules

Thrombospondin-1
Chain: A
Length: 215 amino acids
Theoretical weight: 23.6 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P07996 (Residues: 19-233; Coverage: 19%)
Gene names: THBS1, TSP, TSP1
InterPro:
CATH: Jelly Rolls
SCOP: Laminin G-like module
Thrombospondin-1 in PDB entry 1z78, assembly 1, front view.
Thrombospondin-1 in PDB entry 1z78, assembly 1, side view.
Thrombospondin-1 in PDB entry 1z78, assembly 1, top view.
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