PDBe 1z3u

X-ray diffraction
2.25Å resolution

Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in Tie2 Recognition

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiopoietin-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 217 amino acids
Theoretical weight: 24.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15123 (Residues: 281-496; Coverage: 45%)
Gene name: ANGPT2
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: C2
Unit cell:
a: 140.218Å b: 94.468Å c: 84.673Å
α: 90° β: 94.47° γ: 90°
R-values:
R R work R free
0.26 0.246 0.278
Expression system: Escherichia coli