Function and Biology

Structure of GTP-Bound Rab22Q64L GTPase in complex with the minimal Rab binding domain of Rabenosyn-5

Source organisms:
Biochemical function: GTP binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF11464
Domain description: Rabenosyn Rab binding domain
Occurring in:
  1. Rabenosyn-5
The deposited structure of PDB entry 1z0j contains 1 copy of Pfam domain PF11464 (Rabenosyn Rab binding domain) in Rabenosyn-5. Showing 1 copy in chain B.

PF00071
Domain description: Ras family
Occurring in:
  1. Ras-related protein Rab-22A
The deposited structure of PDB entry 1z0j contains 1 copy of Pfam domain PF00071 (Ras family) in Ras-related protein Rab-22A. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001806
Domain description: Small GTPase
Occurring in:
  1. Ras-related protein Rab-22A
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Ras-related protein Rab-22A
IPR021565
Domain description: Rabenosyn, Rab binding domain
Occurring in:
  1. Rabenosyn-5
IPR036531
Domain description: Rabenosyn, Rab binding domain superfamily
Occurring in:
  1. Rabenosyn-5
IPR005225
Domain description: Small GTP-binding protein domain
Occurring in:
  1. Ras-related protein Rab-22A

Structure domains

CATH CATH domains
4.10.860.20
Class: Few Secondary Structures
Architecture: Irregular
Topology: DNA Excision Repair, Uvrb; Chain A
Homology: Rabenosyn, Rab binding domain
Occurring in:
  1. Rabenosyn-5
The deposited structure of PDB entry 1z0j contains 1 copy of CATH domain 4.10.860.20 (DNA Excision Repair, Uvrb; Chain A) in Rabenosyn-5. Showing 1 copy in chain B.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Ras-related protein Rab-22A
The deposited structure of PDB entry 1z0j contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Ras-related protein Rab-22A. Showing 1 copy in chain A.
SCOP SCOP annotations
140126
Class: All alpha proteins
Fold: Long alpha-hairpin
Superfamily: Rabenosyn-5 Rab-binding domain-like
Occurring in:
  1. Rabenosyn-5
The deposited structure of PDB entry 1z0j contains 1 copy of SCOP domain 140126 (Rabenosyn-5 Rab-binding domain-like) in Rabenosyn-5. Showing 1 copy in chain B.
52592
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. Ras-related protein Rab-22A
The deposited structure of PDB entry 1z0j contains 1 copy of SCOP domain 52592 (G proteins) in Ras-related protein Rab-22A. Showing 1 copy in chain A.