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X-ray diffraction
2Å resolution

GppNHp bound Rab11 GTPase

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-11A Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 20.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62491 (Residues: 8-175; Coverage: 78%)
Gene names: RAB11, RAB11A
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: I422
Unit cell:
a: 73.946Å b: 73.946Å c: 148.197Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.178 0.228
Expression system: Escherichia coli