1yxj

X-ray diffraction
1.78Å resolution

Crystal structure of human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) at low pH

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxidized low-density lipoprotein receptor 1, soluble form Chains: A, B
Molecule details ›
Chains: A, B
Length: 130 amino acids
Theoretical weight: 15.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P78380 (Residues: 143-271; Coverage: 47%)
Gene names: CLEC8A, LOX1, OLR1
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL40B2
Spacegroup: P212121
Unit cell:
a: 62.636Å b: 68.828Å c: 79.133Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.234
Expression system: Escherichia coli BL21(DE3)