X-ray diffraction
3.1Å resolution

Crystal Structure of Succinylglutamate Desuccinylase from Escherichia coli, Northeast Structural Genomics Target ET72.

Source organism: Escherichia coli
Entry authors: Forouhar F, Yong W, Kuzin AP, Ciano M, Acton TB, Montelione GT, Tong L, Hunt JF, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reaction catalysed:
N-succinyl-L-glutamate + H(2)O = succinate + L-glutamate
Biochemical function:
Cellular component:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Succinylglutamate desuccinylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 335 amino acids
Theoretical weight: 37.81 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
  • Canonical: P76215 (Residues: 1-322; Coverage: 100%)
Gene names: JW1733, astE, b1744, ydjS
Sequence domains: Succinylglutamate desuccinylase / Aspartoacylase family
Structure domains: Zn peptidases

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: I422
Unit cell:
a: 146.804Å b: 146.804Å c: 209.449Å
α: 90° β: 90° γ: 90°
R R work R free
0.23 0.227 0.289
Expression system: Escherichia coli