X-ray diffraction
1.8Å resolution

Maltose-binding protein fusion to a C-terminal fragment of the V1a vasopressin receptor


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Maltose/maltodextrin-binding periplasmic protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 366 amino acids
Theoretical weight: 40.25 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
Gene names: JW3994, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II
Vasopressin V1a receptor Chains: M, N
Molecule details ›
Chains: M, N
Length: 84 amino acids
Theoretical weight: 9.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P37288 (Residues: 361-361, 362-418; Coverage: 14%)
Gene names: AVPR1, AVPR1A
Sequence domains: Domain of unknown function (DUF1856)

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P21
Unit cell:
a: 51.102Å b: 66.557Å c: 115.723Å
α: 90° β: 95.99° γ: 90°
R R work R free
0.196 0.199 0.225
Expression system: Escherichia coli BL21