Function and Biology

Novel Ubiquitin-Conjugating Enzyme

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 2.3.2.23: E2 ubiquitin-conjugating enzyme

Reaction catalysed:
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
Systematic name:
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase
Alternative Name(s):
  • UBC
  • Ubiquitin-carrier-protein E2
  • Ubiquitin-conjugating enzyme E2

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR000608
Domain description: Ubiquitin-conjugating enzyme E2
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 U
IPR016135
Domain description: Ubiquitin-conjugating enzyme/RWD-like
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 U
IPR023313
Domain description: Ubiquitin-conjugating enzyme, active site
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 U

Structure domain

CATH CATH domain
3.10.110.10
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin Conjugating Enzyme
Homology: Ubiquitin Conjugating Enzyme
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 U
1 copy of CATH domain 3.10.110.10 (Ubiquitin Conjugating Enzyme) in Ubiquitin-conjugating enzyme E2 U in PDB 1yrv.
SCOP SCOP annotation
54496
Class: Alpha and beta proteins (a+b)
Fold: UBC-like
Superfamily: UBC-like
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 U
1 copy of SCOP domain 54496 (UBC-related) in Ubiquitin-conjugating enzyme E2 U in PDB 1yrv.