Structure analysis

Crystal structure of beta14,-galactosyltransferase mutant ARG228Lys in complex with alpha-lactalbumin in the presence of UDP-galactose and Mn

X-ray diffraction
1.9Å resolution
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 17000 Å2
Buried surface area: 4100 Å2
Dissociation area: 1,000 Å2
Dissociation energy (ΔGdiss): -10 kcal/mol
Dissociation entropy (TΔSdiss): 12 kcal/mol
Interface energy (ΔGint): -30 kcal/mol
Symmetry number: 1
Assembly 2
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Multimeric state: hetero dimer

Binding statistics and energies are not available for this assembly

Macromolecules

Chains: A, C
Length: 123 amino acids
Theoretical weight: 14.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P29752 (Residues: 21-143; Coverage: 100%)
Gene name: Lalba
Pfam: C-type lysozyme/alpha-lactalbumin family
InterPro:
CATH: Lysozyme
SCOP: C-type lysozyme

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