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Human Oxidized Low Density Lipoprotein Receptor LOX-1 Dioxane Complex

X-ray diffraction
1.4Å resolution
PDB entry 1ypq coloured by chain, front view.
PDB entry 1ypq coloured by chain, side view.
PDB entry 1ypq coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Oxidized low-density lipoprotein receptor 1, soluble form
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Multimeric state: homo dimer
Accessible surface area: 13512.56 Å2
Buried surface area: 2203.43 Å2
Dissociation area: 1,030.59 Å2
Dissociation energy (ΔGdiss): 3.85 kcal/mol
Dissociation entropy (TΔSdiss): 11.74 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-160260

Macromolecules

Oxidized low-density lipoprotein receptor 1
Chains: A, B
Length: 135 amino acids
Theoretical weight: 15.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P78380 (Residues: 136-270; Coverage: 50%)
Gene names: CLEC8A, LOX1, OLR1
Pfam: Lectin C-type domain
InterPro:
CATH: Mannose-Binding Protein A, subunit A
SCOP: C-type lectin domain
Oxidized low-density lipoprotein receptor 1 in PDB entry 1ypq, assembly 1, front view.
Oxidized low-density lipoprotein receptor 1 in PDB entry 1ypq, assembly 1, side view.
Oxidized low-density lipoprotein receptor 1 in PDB entry 1ypq, assembly 1, top view.
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