X-ray diffraction
2.5Å resolution

crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide

Source organism: Homo sapiens
Entry authors: Patskovsky YV, Patskovska LN, Listowsky I, Almo SC

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glutathione S-transferase Mu 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 218 amino acids
Theoretical weight: 25.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P09488 (Residues: 1-218; Coverage: 100%)
Gene names: GST1, GSTM1
Structure domains:

Ligands and Environments

Cofactor: Ligand GSH 3 x GSH
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 178.64Å b: 51.41Å c: 93.82Å
α: 90° β: 122.47° γ: 90°
R R work R free
0.24 0.23 0.264
Expression system: Escherichia coli BL21(DE3)